Neem (Azadirachta indica) based preparations have been widely used for centuries as traditional medicine for their antimicrobial, antiulcer, anti-inflammatory, antihelminthic, antidiabetic, immunomodulatory properties. Neem leaf is rich in phytochemicals that are known to exert pleiotropic health effects. Neem leaf has been traditionally used in Ayurveda as Jvara to help relieve fever, as Vrana to treat minor cuts and burns, to relieve itching associated with skin conditions such as eczema.