- Offers balance of key fat-soluble vitamins, A, D, and K, critical to bone health
- Contains vitamin K2 (MK-7), the most bioactive and long-lasting form
- K2 (MK-7) helps increase vertebral bone mineral density among postmenopausal women
- Provides vitamin D3 effective in maintaining blood levels of 25-OH vitamin D23
- Optimal form of vitamin A, palmitate
- Suitable for vegetarians
Vitamin K2, D3 &A provides clinically relevant doses of the three fat-soluble vitamins essential to optimal bone health. Although needed for cardiovascular health, blood sugar regulation, immune function, and inflammation control, vitamins A, D, and K2 have complementary physiological bone-related functions, such as modulating gene expression in osteoblasts and carboxylating osteocalcin, an enzyme needed for bone formation. This is exemplified by a reduction in undercarboxylated osteocalcin and an increase in bone mineral density (BMD) in postmenopausal women when vitamin K is added to vitamin D supplementation.
Vitamin D has diverse and significant functions in multiple body systems, and widespread deficiency magnifies these crucial roles. Supplementation is associated with a well-established reduction in osteoporotic fracture. Correcting a vitamin D deficiency is critical when supplementing with vitamin A, as vitamin A appears to promote bone health if vitamin D levels are adequate. Vitamin K is now recognized as being necessary not only for coagulation, but for the carboxylation of enzymes critical for both bone and blood vessel health. Indeed, meta-analysis has shown improvement in vertebral BMD and reduction in fracture among post-menopausal women with osteoporosis, while controlled trial data shows a reduction in the age-related decline in BMD among healthy postmenopausal women. The naturally derived MK-7 form in Vitamin K2, D3 &A has a longer half-life than any other form.
Each Serving (4 Drops [0.25 ml]) Contains:
Vitamin A (Palmitate) 500 IU (151 mcg RAE)
Vitamin D3 (Cholecalciferol) 1000 IU (25 mcg)
Vitamin K2 (Menaquinone-7) (MK-7) (natto bean) 50 mcg
Non-Medicinal Ingredients: Medium chain triglycerides, organic flaxseed oil, natural vitamin E (non-GMO sunflower oil), natural vanilla flavour.
1 serving (0.25 ml) per day or as directed by a health care practitioner.
1 serving (0.25 ml) per day or as directed by a health care practitioner. Drug Interactions: Vitamin K may antagonize the effect of some anticoagulant medications, and concurrent use should be medically supervised. When taken with a thiazide medication (diuretic), vitamin D may increase the risk for hypercalcemia. Also, vitamin D may improve insulin sensitivity and lower blood pressure, requiring a reduction in dosage of hypertension and/or diabetic medications. Vitamin A should not be taken with other synthetic retinoids, such as acitretin or bexarotene.