{"title":"Practitioner Recommended - Best NAC Supplements","description":"\u003cp\u003eN-Acetyl Cysteine (NAC) is a powerful antioxidant that supports glutathione production, liver detoxification, and respiratory health. Explore top practitioner-grade options from  Bioclinic Naturals, Designs for Health, NFH, and CanPrev, formulated for optimal absorption and daily antioxidant support.\u003c\/p\u003e","products":[{"product_id":"aor-nac","title":"AOR NAC","description":"\u003cul\u003e \u003cli\u003ePromotes respiratory health helps clear excess mucus\u003c\/li\u003e \u003cli\u003eProtects the liver by boosting glutathione levels\u003c\/li\u003e \u003cli\u003eSupports detoxification\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eN-Acetyl-L-Cysteine or N-A-C is an acetylated form of the amino acid cysteine. Cysteine is the most important precursor to glutathione (GSH) the most critical antioxidant produced in the body. Glutathione helps chelate toxins and heavy metals from the body. N-A-C is approved as a drug in some European jurisdictions for use in preventing liver damage from acetaminophen overdose. It has been used for over 30 years for respiratory health providing some relief to those suffering from chronic respiratory conditions such as the annoying post-nasal drip sinusitis chronic bronchitis the congenital disease cystic fibrosis and even life-threatening conditions such as COPD.  N-A-C also promotes cardiovascular health due to its unique ability to inhibit levels of a specific lipoprotein called Lp(a) a marker of heart disease.\u003c\/p\u003e\u003cp\u003eAcetylated cysteine is better absorbed than regular cysteine. AOR’s N-A-C is an excellent choice for those looking for a single supplement to promote overall health including cellular protection and cardiovascular health. People suffering from chronic respiratory conditions may also benefit from regular use of N-A-C.\u003c\/p\u003e","brand":"AOR","offers":[{"title":"240 capsules","offer_id":40277871493143,"sku":"AOR04428","price":54.53,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/products\/aor-nac.png?v=1662420775"},{"product_id":"canprev-nac","title":"CanPrev NAC+","description":"\u003cul\u003e \u003cli\u003eFor cellular protection against free radical damage\u003c\/li\u003e \u003cli\u003e600 mg of N-Acetyl-L-Cysteine\u003c\/li\u003e \u003cli\u003ePlus L-Glycine and selenium for added cellular support\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eNAC+ was designed for superior defence against oxidative stress from over-exercise  pollutants and respiratory conditions. It features 600mg of N-Acetyl-L-Cysteine (NAC) with L-Glycine and selenium for enhanced cell protection against free radicals.\u003c\/p\u003e\u003cp\u003eNAC has mucolytic properties that help to relieve symptoms of chronic bronchitis caused by oxidative stress. Taking NAC may improve phlegm consistency in people with chronic obstructive pulmonary disease (COPD) and help to decrease flare-ups. Studies suggest that NAC may have a positive effect on reducing homocysteine levels in cases where high plasma homocysteine levels are present.\u003c\/p\u003e\u003cp\u003eBoth N-Acetyl-L-Cysteine and L-Glycine are precursors to glutathione (GSH) – our critical intracellular antioxidant for the liver and brain. GSH scavenges free radicals reducing inflammation and protecting cell mitochondria. When combined with the powerhouse mineral selenium Vitamin E levels and glutathione peroxidase levels are further enhanced for cellular health and protection.\u003c\/p\u003e\u003cp\u003eWhether you’re an athlete exposed to high levels of free radicals fighting off a lingering respiratory condition or looking to boost your body’s detoxification abilities NAC+ offers a superior support system for cellular protection.\u003c\/p\u003e","brand":"CanPrev","offers":[{"title":"120 veggie capsules","offer_id":40277876867095,"sku":"195519","price":29.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/products\/1324841_CanPrev_NAC.png?v=1749228863"},{"product_id":"nfh-nac-sap","title":"NFH NAC SAP","description":"\u003cspan\u003eN-Acetylcysteine (NAC) is a precursor to glutathione synthesis and also acts on its own to reduce the effects of reactive oxygen species. NAC also has mycolytic properties and decreases viscosity of lung secretions. NAC has been shown by studies to have a protective effect on the liver and has been used to manage acetaminophen overdose, due to its ability to enhance hepatic and mitochondrial levels of glutathione and by supporting the mitochondrial energy metabolism.\u003c\/span\u003e","brand":"NFH","offers":[{"title":"90 Capsules","offer_id":40560205725719,"sku":"NFH1045","price":37.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/1415-NAC-SAP-90-capsules.jpg?v=1749226622"},{"product_id":"bioclinic-naturals-nac-500-mg","title":"Bioclinic Naturals NAC 500 mg","description":"\u003cul class=\"feature-list\" data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSupports glutathione synthesis, key cellular antioxidant and conjugator of numerous environmental toxins\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eImproves endothelial function and supports nitric oxide synthesis\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e500 mg NAC per capsule allows for easy and therapeutic dosing levels\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eStable and well-absorbed form of the easily oxidized amino acid L-cysteine\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eEvidence base for diverse clinical uses\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eN-Acetyl-L-Cysteine (NAC) is known to have diverse physiological and therapeutic benefits, attributed largely to its antioxidant, anti-inflammatory and mucolytic effects. It is well-accepted to increase the critical intracellular antioxidant glutathione, by supplying a stable form of L-cysteine, the rate-limiting factor for glutathione synthesis.\u003cspan\u003e \u003c\/span\u003eThe number of conditions with altered glutathione homeostasis continues to grow, including not only cardiovascular, neurodegenerative, pulmonary and age-related diseases, but there is also a growing clinical recognition of metabolic disturbances linked to environmental toxin exposure, such as diabetes and persistent organic pollutants.\u003cspan\u003e \u003c\/span\u003eBy restoring glutathione levels, NAC also is well established as the most effective therapy for acetaminophen toxicity.\u003c\/p\u003e\n\u003cp\u003eAdditionally, NAC’s ability to cleave disulfide bonds provides efficacy as a mucolytic agent, with clinical benefit for individuals with COPD and pulmonary fibrosis.\u003cspan\u003e \u003c\/span\u003eBreaking disulfide bonds may also be the same mechanism by which it lowers homocysteine and improves endothelial function in coronary artery disease.\u003cspan\u003e \u003c\/span\u003eNAC has immunomodulating and anti-inflammatory effects, improving influenza symptomology and SLE disease activity.\u003cspan\u003e \u003c\/span\u003eBy modulating glutamatergic and neurotropic pathways, NAC also has shown benefit for schizophrenia, bipolar disorder and autism.\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 V-caps","offer_id":40625112973335,"sku":"9524","price":17.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/NAC.jpg?v=1749226096"},{"product_id":"bioclinic-naturals-nac-ala","title":"Bioclinic Naturals NAC \u0026 ALA","description":"\u003cul data-mce-fragment=\"1\" class=\"feature-list\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eProvides clinically relevant doses of N-acetyl-L-cysteine (NAC) and alpha-lipoic acid (ALA)\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eNAC and ALA have direct antioxidant action and enhance the synthesis and regeneration of glutathione, the key cellular antioxidant\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSupports mitochondrial function as well as phase II antioxidant enzyme upregulation\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eTargets central mediators of inflammation\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eImproves endothelial function and supports nitric oxide synthesis\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eReduces hyperglycemia-associated damage\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSuitable for vegetarians\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eNAC and ALA are highly complementary nutrients, critical to cellular function and mitigation of hyperglycemia-associated damage. NAC drives the synthesis of glutathione, often depleted in cardiovascular diseases and metabolic and oxidative stress conditions.\u003cspan\u003e \u003c\/span\u003eNAC also has direct antioxidant activity, restores pools of intracellular thiols, and has an anti-inflammatory effect, mediated via inhibition of nuclear factor kappa B (NF-κB).\u003cspan\u003e \u003c\/span\u003eGlutathione is needed for the detoxification of many persistent organic pollutants, compounds known to impair mitochondrial function, adipose tissue metabolism, and pancreatic islet cell function\u003cspan style=\"font-size: 11.6667px;\"\u003e.\u003c\/span\u003e\u003cspan\u003e \u003c\/span\u003eIn addition to glutathione support, NAC enhances antioxidant protection through multiple pathways, including upregulation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and phosphoinositide 3-kinase\/protein kinase B (PI3K\/AKT) activation, suggesting a significant potential to mitigate pathology due to oxidative stress.\u003cspan\u003e \u003c\/span\u003eClinical trials have shown that NAC restores intraplatelet glutathione levels in certain populations – a marker of atherothrombotic risk – reduces homocysteine, and improves endothelial function in coronary artery disease (at doses of 600–1800 mg\/day).\u003c\/p\u003e","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":40625119330327,"sku":"9525","price":30.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/NAC_ALA.png?v=1749226097"},{"product_id":"designs-for-health-n-acetyl-cysteine","title":"Designs For Health N-Acetyl-Cysteine","description":"\u003cspan\u003eN-Acetyl-Cysteine (NAC) is an amino acid that is a precursor to glutathione, the body’s most powerful antioxidant, and helps promote optimal detoxification. NAC is heavily researched for its role in optimizing lung health, and for rapid recovery after workouts. It is also beneficial for protection against normal exposure to heavy metals.\u003c\/span\u003e","brand":"Designs for Health","offers":[{"title":"120 Vegetarian Capsules","offer_id":40992515227671,"sku":"NAC120-CN","price":60.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/nac120-cn_300cc.png?v=1749225852"},{"product_id":"pure-encapsulations-nac-glycine-powder","title":"Pure Encapsulations NAC + Glycine powder","description":"\u003cul\u003e\n\u003cli\u003eRestores and promotes glutathione synthesis\u003c\/li\u003e\n\u003cli\u003eEnhances immune \u0026amp; antioxidant defences\u003c\/li\u003e\n\u003cli\u003eReduces oxidative stress\u003c\/li\u003e\n\u003cli\u003eSupports the body's natural detoxification process\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eCysteine and glycine are both necessary precursors for glutathione (GSH) synthesis, and co-supplementation of these nutrients promotes intracellular glutathione levels. Glutathione is one of the main endogenous antioxidants, acting in the body to recycle other antioxidants and protect the body from free radicals, as well as support detoxification. It is found in virtually every cell of the body and plays a critical role in cell function. Increased glutathione levels have been linked to supporting a reduction in oxidative stress.\u003c\/p\u003e\n\u003c!----\u003e","brand":"Pure Encapsulations","offers":[{"title":"159 g","offer_id":41335754162199,"sku":"NGY1C-C","price":37.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/Capture_430x_9642a60c-b305-4954-b478-48e03a9c864f.webp?v=1749225662"},{"product_id":"cyto-matrix-nac-matrix","title":"Cyto-Matrix NAC-Matrix","description":"\u003cul\u003e\n\u003cli\u003e600mg of N-Acetyl-LCysteine per capsule with added glycine and selenium to upregulate the endogenous production of glutathione and detoxification systems\u003c\/li\u003e\n\u003cli\u003eSelenium is provided in a glycinate chelate for optimal absorption\u003c\/li\u003e\n\u003cli\u003eIndicated in cases of environmental toxin exposure, bronchitis and respiratory illness, acne vulgaris, polycystic ovarian syndrome (PCOS) and health conditions with oxidative stress\u003c\/li\u003e\n\u003cli\u003eNAC matrix\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Cyto-Matrix","offers":[{"title":"90 v-caps","offer_id":41790340530199,"sku":"193181","price":27.84,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/NACMatrix-90vcaps.png?v=1749225650"},{"product_id":"arcwell-nac-n-acetyl-l-cysteine","title":"Arcwell NAC (N-Acetyl-L-Cysteine)","description":"\u003cul\u003e\n\u003cli\u003eSupports respiratory health \u0026amp; relieves symptoms of chronic bronchitis\u003c\/li\u003e\n\u003cli\u003eEasily mixable powder for flexible, high-purity dosing\u003c\/li\u003e\n\u003cli\u003eA precursor to glutathione, a potent intracellular antioxidant\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003eArcwell® NAC Powder delivers pure, pharmaceutical-grade N-Acetyl-L-Cysteine (NAC) in a convenient, unflavored powder form — ideal for those seeking clean, customizable support for immune function, detoxification, and respiratory health.\u003c\/p\u003e\n\u003cp\u003eNAC is a stable form of the amino acid cysteine, which your body converts into glutathione, a powerful intracellular antioxidant. Glutathione plays a vital role in protecting cells from oxidative stress, environmental toxins, and free radical damage.\u003c\/p\u003e\n\u003ch2\u003eResearch shows NAC helps:\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eRelieve symptoms of chronic bronchitis\u003c\/li\u003e\n\u003cli\u003eBreak down and clear excess mucus in the lungs (especially in cases of cystic fibrosis or COPD)\u003c\/li\u003e\n\u003cli\u003eReduce the frequency and severity of flu-like symptoms\u003c\/li\u003e\n\u003cli\u003eSupport immune response and DNA integrity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eAs a powder, Arcwell® NAC offers maximum flexibility for those who prefer to tailor their dosage — ideal for wellness practitioners, high-performance users, or those on therapeutic regimens.\u003c\/p\u003e","brand":"Arcwell","offers":[{"title":"60 grams","offer_id":45159646330903,"sku":null,"price":37.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/amazon_nac-60g-powder-01_9d0db5fd-cb46-469e-be8a-d2ef6014568d.webp?v=1779528493"},{"product_id":"arcwell-nmn-powder","title":"Arcwell NMN Powder","description":"\u003cp\u003e\u003cspan\u003eNMN (beta-Nicotinamide Mononucleotide) is a direct precursor to NAD+, a vital coenzyme naturally produced in your body. With age, NAD+ levels can decline by up to 50%, leading to noticeable effects on your overall vitality. However, with NMN supplementation, you can restore intracellular NAD+ levels, triggering remarkable transformations that enhance survival and well-being, including boosting energy production and upregulating cellular repair. NMN has been demonstrated to support exercise performance by increasing NAD+ level in human skeletal muscles.* \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eArcwell® NMN is in a stable form with high purity over 99% and a dosage that has proven its efficacy.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e250mg per scoop\u003c\/span\u003e\u003c\/p\u003e","brand":"Arcwell","offers":[{"title":"15 gram","offer_id":45159656816663,"sku":null,"price":89.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/arcwell-nmn-powder-15g.1778941360.png?v=1779528493"},{"product_id":"arcwell-fisetin-100mg","title":"Arcwell Fisetin, 100mg","description":"\u003cp\u003e\u003cspan\u003eFisetin, a natural flavonoid abundant in strawberries, cucumbers, apples, onions, and more, is renowned for its potent senolytic and anti-inflammatory properties. Fisetin holds a notable reputation for its role in eliminating senescent cells, aka \"Zombie cells”. These senescent cells, which accumulate in the body as a primary driver of aging, trigger inflammation and impair cellular function, heightening the risk of age-related diseases.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eMoreover, preclinical studies have shown promising effects of fisetin on brain cells and cognitive pathways. As a bioflavonoid antioxidant, it helps preserve glutathione levels and mitochondrial function, especially during oxidative stress. Its ability to cross the blood-brain barrier suggests potential support for neuronal health.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eFisetin, recommended at a dosage of 100 mg per day, has been deemed safe. Promising results from human clinical trials suggest its potential as a complementary therapy, particularly for reducing inflammation.\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eArcwell® Fisetin guarantees you high purity (\u0026gt; 98%) and a dosage that has proven its efficacy.\u003c\/span\u003e\u003c\/p\u003e","brand":"Arcwell","offers":[{"title":"30 caps","offer_id":45159706296343,"sku":null,"price":49.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/Fisetin_100mg30caps_-_Arcwell.webp?v=1779528493"}],"url":"https:\/\/www.vitamintree.ca\/collections\/practitioner-recommended-best-nac-supplements.oembed","provider":"Vitamin Tree","version":"1.0","type":"link"}