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Elevated homocysteine levels are often observed in the elderly and in individuals with compromised nutrition, gastrointestinal disorders or a genetic tendency for hyperhomocysteinemia. \u003c\/span\u003e\u003cstrong\u003eMethyl SAP\u003c\/strong\u003e\u003cspan\u003e provides a combination of scientifically supported doses of B vitamins (folate, vitamin B\u003c\/span\u003e\u003csub\u003e6\u003c\/sub\u003e\u003cspan\u003e, vitamin B\u003c\/span\u003e\u003csub\u003e12\u003c\/sub\u003e\u003cspan\u003e).\u003c\/span\u003e\u003c\/p\u003e","brand":"NFH","offers":[{"title":"60 caps","offer_id":40367596568599,"sku":"NFH1010","price":39.7,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/products\/1010-Methyl-SAP-60-capsules.jpg?v=1749228317"},{"product_id":"pure-encapsulations-b12-liquid","title":"Pure Encapsulations B12 1000 Liquid","description":"\u003cul\u003e \u003cli\u003eHelps the body metabolize nutrients and form red blood cells\u003c\/li\u003e \u003cli\u003eConvenient liquid format free of added colour or artificial sugars\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eMethylcobalamin is an activated highly bioavailable form of vitamin B12 which acts as the principal circulating form of cobalamin in the body. In general vitamin B12 works with folate to promote red blood cell formation. Additionally vitamin B12 is an important cofactor for energy metabolism. One vitamin B12-dependent enzyme is methylmalonyl-CoA mutase which is involved in the formation of succinyl-CoA a key Krebs cycle intermediate. Vitamin B12 is also a vital component of the methionine synthase pathway.\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"30 mL","offer_id":40367682355223,"sku":"B12LC-C","price":29.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/products\/3195634_B12LC___C.png?v=1749228268"},{"product_id":"pure-encapsulations-b-complex-plus","title":"Pure Encapsulations B-Complex Plus","description":"\u003cdiv\u003e\u003cdiv\u003e\n\u003cdiv\u003eBalanced B vitamin formula\u003c\/div\u003e\n\u003cdiv\u003e \u003c\/div\u003e\n\u003cdiv\u003e \u003c\/div\u003e\n\u003c\/div\u003e\u003c\/div\u003e","brand":"Pure Encapsulations","offers":[{"title":"60 veggie capsules","offer_id":40367682584599,"sku":"BCP6C-C","price":32.5,"currency_code":"CAD","in_stock":true},{"title":"120 veggies capsules","offer_id":44088800706583,"sku":"BCP1C-C","price":54.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/products\/3195599_BCP6C___C.png?v=1749228268"},{"product_id":"pure-encapsulations-puregenomics-b-complex","title":"Pure Encapsulations PureGenomics B-Complex","description":"\u003cp\u003eB-complex targeting common genetic polymorphisms\u003c\/p\u003e\u003cul\u003e \u003cli\u003eComprehensive B vitamin supplement\u003c\/li\u003e \u003cli\u003eProvides activated B vitamins including pyridoxal-5-phosphate riboflavin-5-phosphate enhanced-retention thiamine derivative benfotiamine and 800 mcg of Metafolin® L-5-methyltetrahydrofolate (L-5-MTHF) per capsule the naturally occurring universally metabolized form of folate\u003c\/li\u003e \u003cli\u003eOffers vitamin B12 in unique blend of adenosylcobalamin and hydroxocobalamin\u003c\/li\u003e \u003cli\u003eMade with hypoallergenic vegan ingredients\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003ePureGenomics™ B-Complex is designed to address the nutrient requirements of common genetic variations in the methylation pathway with a unique blend of B vitamins in highly researched and activated forms. Folate is offered in this formula as Metafolin® L-5-methyltetrahydrofolate (L-5-MTHF) the universally metabolized and biologically active form of folate providing support for individuals with genetic variations in the MTHFR gene. Vitamin B12 is offered as a combination of hydroxocobalamin and adenosylcobalamin. Hydroxocobalamin is a precursor form of vitamin B12 converted in the body to both methylcobalamin and adenosylcobalamin. Adenosylcobalamin is an activated form stored in the mitochondria of cellular tissues. It is a key cofactor in carbohydrate metabolism for the enzyme methylmalonyl-CoA mutase which is used to produce succinyl-CoA. Optimal levels of vitamin B12 also support normal immune function. Benfotiamine is a lipid-soluble enhanced-retention thiamine derivative. This formula also includes the methyl donor choline which helps to support liver function.\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"120 caps","offer_id":40367682912279,"sku":"PGB1C-C","price":75.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/products\/2356847_Pure_PureGeniomicsBComplex.jpg?v=1749228268"},{"product_id":"xymogen-methyl-protect","title":"XYMOGEN Methyl Protect","description":"\u003cul\u003e\t\u003cli\u003eSupports Cardiovascular and Neurological Health*\u003c\/li\u003e\t\u003cli\u003eSupports the Maintenance of Healthy Homocysteine Levels Already Within Normal Range*\u003c\/li\u003e\t\u003cli\u003eSupports Healthy Methylation of Estrogen Dopamine Epinephrine Heavy Metals and Environmental Toxins*\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eMethyl Protect® is a comprehensive formula designed to support optimal methylation and help maintain healthy homocysteine levels already within normal range. It features five key nutrients that are involved in homocysteine metabolism: folate as calcium folinate and Quatrefolic® for increased bioactivity; trimethylglycine; and vitamins B12 B6 and B2. These five nutrients provided in activated forms support enhanced methylation and overall cardiovascular health.*\u003c\/p\u003e","brand":"XYMOGEN","offers":[{"title":"60 capsules","offer_id":40477054337047,"sku":"80030245","price":53.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/300000493-methyl-protect-60-capsules.png?v=1770306005"},{"product_id":"ortho-molecular-products-methyl-b-complex","title":"Ortho Molecular Products - Methyl B Complex","description":"Methyl B Complex contains eight essential B vitamins along with choline inositol and folate as Quatrefolic™ - 100% 5-MTHF the biologically active form of folic acid for optimal methylation.\u003cul\u003e\t\u003cli\u003eHelps to maintain the body's ability to metabolize nutrients\u003c\/li\u003e\t\u003cli\u003eHelps to prevent biotin vitamin B12 vitamin B6 thiamine riboflavin and pantothenic acid deficiencies\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eFolate\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eFolate is a water soluble member of the B complex vitamins that is critical for maintaining optimal methylation. Folate is found naturally in foods such as fruits and dark leafy vegetables but can be easily destroyed by cooking or processing. Additionally enzyme defects malabsorption and congenital deficiency of 5-methylenetetrahydrofolate reductase (5-MTHFR) an enzyme required for the conversion of folic acid to its bioactive form 5-methyltetrahydrofolate (5-MTHF) can result in an impaired ability to activate folic acid. In individuals with a genetic defect of this enzyme supplementation with 5-MTHF has been shown to be beneficial. 5-MTHF is required as a methyl group donor for the production of mood regulating neurotransmitters such as serotonin the synthesis of melatonin as well as DNA production and repair. 5-MTHF also donates its methyl group to vitamin B12 (cobalamin) forming methylcobalamin. Methylcobalamin helps convert the amino acid metabolite homocysteine into the amino acid methionine.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eThiamine\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eWhile naturally abundant in whole grains thiamine is lost in many of the over-processed grains commonly consumed today. Thiamine is an essential co-factor in the production of ATP in the cells' Kreb's cycle and is also needed for the metabolism of fats proteins and carbohydrates.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eRiboflavin\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eRiboflavin is a precursor to flavin adenine dinucleodtide (FAD) and flavin mononucleotide (FMN) both of which are central to energy production and intermediary metabolism. Riboflavindepleted cells have been found to display signs of greater oxidative stress and disrupted energy generation.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eVitamin B6\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eVitamin B6 is involved in over 100 enzymatic reactions in the body and is essential in methylation for the breakdown of homocysteine.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eVitamin B12\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eVitamin B12 found only in organ meats seafood and egg yolks often becomes deficient in vegan and vegetarian diets. The vitamin is essential for the metabolism of fats and carbohydrates the synthesis of proteins and energy metabolism.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBiotin\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eSynthesized by the bacteria in the gut in addition to certain foods biotin and its cofactors are involved in metabolism of fatty acids amino acids and utilization of B vitamins.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePantothenic Acid\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003ePantothenic acid and its biologically active derivative CoA are essential to the synthesis of fatty acids membrane phospholipids amino acids steroid hormones and energy production.\u003c\/p\u003e","brand":"Ortho Molecular Products","offers":[{"title":"60 capsules","offer_id":40477056696343,"sku":"360060CAN","price":39.3,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/products\/4387902_METHYL-B-COMPLEX-OMP.jpg?v=1673713972"},{"product_id":"nfh-b-complex-sap","title":"NFH B-Complex SAP","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eB‑Complex SAP\u003c\/strong\u003e is a synergistic combination of essential B vitamins designed to support healthy metabolism. B vitamins are water-soluble cofactors that are vital for energy production, formation of red blood cells and tissue, nutrient metabolism, and normal function of the immune system.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eB vitamins work together to improve stress levels and the proper functioning of the nervous system. \u003cstrong data-mce-fragment=\"1\"\u003eB‑Complex SAP\u003c\/strong\u003e\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003econtains active forms of vitamins B2 (riboflavin-5′-phosphate) and B6 (pyridoxal-5′-phosphate) for high bioavailability.\u003c\/p\u003e","brand":"NFH","offers":[{"title":"60 Capsules","offer_id":40488764211223,"sku":"NFH1017","price":29.9,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/products\/1017-B-Complex-SAP-60-capsules.jpg?v=1749227916"},{"product_id":"pure-encapsulations-adenosyl-hydroxy-b12","title":"Pure Encapsulations Adenosyl\/Hydroxy B12","description":"Offers vitamin B12 blend for energy and immune support\u003cbr data-mce-fragment=\"1\"\u003e\n\u003cul\u003e\n\u003cli\u003eVegan\u003c\/li\u003e\n\u003cli\u003eVegetarian\u003c\/li\u003e\n\u003cli\u003eGMO Free\u003c\/li\u003e\n\u003cli\u003eGluten Free\u003c\/li\u003e\n\u003cli\u003eHelps in energy metabolism and red blood cell formation\u003c\/li\u003e\n\u003cli\u003eAids in the normal function of the immune system\u003c\/li\u003e\n\u003cli\u003eConvenient capsule format\u003c\/li\u003e\n\u003c\/ul\u003e\nAdenosyl\/Hydroxy B12 is a unique blend of adenosylcobalamin and hydroxycobalamin, offering unmethylated vitamin B12 to support energy production and normal immune function. Hydroxycobalamin is a precursor form of vitamin B12 converted in the body to both methylcobalamin and adenosylcobalamin. It is similar to cyanocobalamin without the cyanide moiety. Adenosylcobalamin is an activated form similar to methylcobalamin. While methylcobalamin is found in the cytosol of cells and predominates in blood and other fluids, adenosylcobalamin is the major form of vitamin B12 stored in the mitochondria of cellular tissues. It is a key cofactor in carbohydrate metabolism for the enzyme methylmalonyl-CoA mutase used to produce succinyl-CoA. Optimal levels also support red blood cell formation and normal immune function.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eRecommended Use: Helps to prevent vi tamin B12 deficiency. Helps to form red blood cells. Helps in energy metabolism in the body and in the no rmal function of the immune system.","brand":"Pure Encapsulations","offers":[{"title":"90 vegetable capsules","offer_id":40501368946711,"sku":"AHB9C-C","price":40.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/products\/Adenosyl.jpg?v=1749227678"},{"product_id":"genestra-liquid-b-complex","title":"Genestra Liquid B Complex","description":"\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eBroad-spectrum B-vitamin complex\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003e• Helps to maintain cognitive function, normal immune function and energy production\u003cbr data-mce-fragment=\"1\"\u003e• Aids in the maintenance of healthy hair, nails and skin\u003cbr data-mce-fragment=\"1\"\u003e• Convenient liquid format\u003cbr data-mce-fragment=\"1\"\u003e• Aids in the maintenance of healthy hair, nails and skin\u003cbr data-mce-fragment=\"1\"\u003e• Great-tasting, natural tangerine-cherry flavour\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eImproved formula\u003c\/strong\u003e• Now available in a 450 ml bottle\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eLiquid B Complex is a delicious combination of seven B vitamins, plus choline and inositol. It provides the adult Recommended Dietary Allowance (RDA) for thiamine, riboflavin, niacinamide, vitamin B\u003csub data-mce-fragment=\"1\"\u003e6\u003c\/sub\u003e, vitamin B\u003csub data-mce-fragment=\"1\"\u003e12\u003c\/sub\u003e, biotin and pantothenic acid. B vitamins play an important role in energy metabolism as cofactors for numerous biochemical reactions in the body.\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eVitamins B\u003csub data-mce-fragment=\"1\"\u003e6\u003c\/sub\u003e, B\u003csub data-mce-fragment=\"1\"\u003e12\u003c\/sub\u003e\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eand riboflavin are particularly critical in the metabolism of the amino acid metabolite homocysteine.\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eVitamin B\u003csub data-mce-fragment=\"1\"\u003e12\u003c\/sub\u003e\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003ehas an additional role helping in the normal function of the immune system and is involved in red blood cell formation alongside vitamin B\u003csub data-mce-fragment=\"1\"\u003e6\u003c\/sub\u003e. In addition, biotin helps maintain cognitive functions as well as healthy hair, nails, mucous membranes and skin. Liquid B Complex also provides choline, a lipotrope that helps support liver function, plus inositol, an important second messenger and component of the phospholipid membrane.\u003c\/p\u003e","brand":"Genestra","offers":[{"title":"450 ml","offer_id":40514611314711,"sku":"02131A","price":62.25,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/products\/liquid-b-complex-02131a.png.mst.webp?v=1749227511"},{"product_id":"designs-for-health-b-supreme","title":"Designs for Health B-Supreme","description":"\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eSupports energy production by helping the body properly utilize amino acids, fats and carbohydrates \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eEncourages optimal mental health, brain activity and feelings of well-being\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003eEssential for sustaining a healthy metabolism (the chemical processes of the body)\u003c\/span\u003e \u003c\/li\u003e\n\u003cli\u003eHelps balance female hormones, especially during pregnancy, menstruation or other key phases in a woman’s life\u003c\/li\u003e\n\u003cli\u003eSupports healthy neurological development in babies and during pregnancy\u003c\/li\u003e\n\u003cli\u003ePromotes the production and maintenance of healthy blood cells and joints\u003c\/li\u003e\n\u003cli\u003eSupports a strong immune system\u003c\/li\u003e\n\u003cli\u003eAssists with the maintenance of healthy blood sugar levels\u003c\/li\u003e\n\u003cli\u003ePossesses antioxidant properties, thus helps fight damage to cell membranes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eThis very powerful B vitamin combination formula supplies most of the B vitamins in their coenzymated forms, so the body does not have to phosphorylate them in order to be used in biochemical reactions. This formula also includes TMG and choline to support methylation.\u003c\/span\u003e\u003c\/p\u003e","brand":"Designs for Health","offers":[{"title":"60 Vegetarian Capsules","offer_id":40520617623575,"sku":"BSP060-CN","price":39.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/products\/bsp060-cn_150cc.png?v=1749227511"},{"product_id":"xymogen-b-activ","title":"Xymogen B-Activ","description":"\u003cul class=\"pi-list-with-icons pi-list-icons-right-open\"\u003e\n\u003cli\u003eVitamin supplement\u003c\/li\u003e\n\u003cli\u003eA factor in the maintenance of good health\u003c\/li\u003e\n\u003cli\u003eHelps the body to metabolize carbohydrates, fats, and proteins\u003c\/li\u003e\n\u003cli\u003eHelps normal growth and development\u003c\/li\u003e\n\u003cli\u003eHelps in tissue formation\u003c\/li\u003e\n\u003cli\u003eHelps to form red blood cells\u003c\/li\u003e\n\u003cli\u003eHelps to support liver function\u003c\/li\u003e\n\u003cli\u003eHelps to prevent folate deficiency in men and non-pregnant and non-breastfeeding women\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"XYMOGEN","offers":[{"title":"90 Vegetarian Capsules","offer_id":40527324807191,"sku":"80032793","price":58.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/300000454-b-activ-90-capsules.png?v=1770305585"},{"product_id":"cyto-matrix-bio-b-matrix-b6","title":"Cyto-Matrix Bio-B Matrix B6","description":"\u003cul class=\"list-disc text-lg leading-relaxed text-gray-600 pl-6\"\u003e\n\u003cli\u003eA B-complex containing a high-dose vitamin B6 blend for improved hormonal detoxification and mood support.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"list-disc list_points text-lg leading-relaxed text-gray-600\"\u003e\n\u003cul\u003e\n\u003cli\u003eA comprehensive balance of B-vitamins in their metabolically active and highly bioavailable forms, including 210mg of vitamin B6 as a blend of pyridoxine HCl and pyridoxal-5-phosphate\u003c\/li\u003e\n\u003cli\u003eIndicated for hormonal balancing and mood support, especially in cases of premenstrual syndrome and premenstrual dysphoric disorder\u003c\/li\u003e\n\u003cli\u003eAdditional indications for carpal tunnel syndrome, hyperhomocysteinemia and nausea\u003c\/li\u003e\n\u003cli\u003eCytoMatrix\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"Cyto-Matrix","offers":[{"title":"60 Vegetable capsules","offer_id":40527358558231,"sku":"193130","price":31.96,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/products\/1646762520_CM-Bio-BMatrixB6-60vcaps-RGB-193130-V1.png?v=1749227320"},{"product_id":"nfh-b5-sap","title":"NFH B5 SAP","description":"\u003cp\u003e\u003cstrong\u003eB5 SAP\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003ehas been formulated to contain a complex of B vitamins (water-soluble cofactors) heavily weighed to B5 (pantothenic acid) to help support energy production, formation of red blood cells and tissue, promote nutrient metabolism, foster normal function of the immune system and support liver function.\u003c\/p\u003e\n\u003cp\u003eB vitamins work together to improve stress levels and the proper functioning of the nervous system. Vitamin B5 is an important part in the formation of coenzyme A, which is essential for several functions necessary to sustain life.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eB5 SAP\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003econtains active forms of vitamins B2 (riboflavin-5′-phosphate) and B6 (pyridoxal-5′-phosphate) for high bioavailability.\u003c\/p\u003e","brand":"NFH","offers":[{"title":"60 Capsules","offer_id":40559900950551,"sku":"1111","price":25.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/1962-B5-SAP-60-capsules.jpg?v=1749226623"},{"product_id":"nfh-b6-sap","title":"NFH B6 SAP","description":"\u003cspan\u003eVitamin B\u003c\/span\u003e\u003csub\u003e6\u003c\/sub\u003e\u003cspan\u003e is involved in a plethora of physiological functions, especially playing key roles in homocysteine metabolism, hemoglobin formation, and neurotransmitter synthesis. \u003c\/span\u003e\u003cspan\u003eIt also acts as a potent antioxidant in the body. \u003c\/span\u003e\u003cstrong\u003eB6 SAP\u003c\/strong\u003e\u003cspan\u003e provides a healthy supplemental dose of vitamin B\u003c\/span\u003e\u003csub\u003e6\u003c\/sub\u003e\u003cspan\u003e, including 10 mg of the active form pyridoxal-5′-phosphate, in a blend of B vitamins and choline to support optimal B\u003c\/span\u003e\u003csub\u003e6\u003c\/sub\u003e\u003cspan\u003e metabolism. \u003c\/span\u003e","brand":"NFH","offers":[{"title":"60 Capsules","offer_id":40559901081623,"sku":"NFH1032","price":34.1,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/1338-B6-SAP-60-capsules.jpg?v=1749226623"},{"product_id":"bioclinic-naturals-b12-methylcobalamin-1000-mcg","title":"Bioclinic Naturals B12 Methylcobalamin - 1000 mcg","description":"\u003cdiv class=\"uses_benefits\" data-mce-fragment=\"1\"\u003e\n\u003cul class=\"feature-list\" data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eMethylcobalamin is the active form of vitamin B12 for maximum benefit \u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSuperior bioavailability to the more common form, cyanocobalamin, which does not convert to enough methylcobalamin to correct some forms of anemia, neurological defects and aging\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eLowers homocysteine levels for protective cardiovascular benefits\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSublingual tablets allow for fast acting delivery system directly into blood stream\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"feature_summary\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003eVitamin B12 is the cofactor in enzymatic reactions with diverse physiological functions. It is required for the conversion of methylmalonyl CoA to succinyl CoA, as well as for the conversion of homocysteine to methionine by methionine synthase, which is then converted into S-adenosylmethionine.\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eA B12 deficiency causes impairments in both of these pathways, disrupting neurological function, including poor formation of myelin nerve sheaths, production of toxic levels of homocysteine, and inefficient energy production in all cells.\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eMethylcobalamin, the principal circulating form of B12 and the one transported into peripheral tissues, has been shown to not only reduce homocysteine, but also to reduce inflammatory factors and the volume of carotid artery plaques among stroke patients, as well as pain, and neuropathy among diabetics.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eCobalamin is also required to remove the methyl group from methyltetrahydrofolate and generate tetrahydrofolate, a necessary step in DNA synthesis. As a consequence, B12 deficiency affects the growth, function, and repair of all cells, the most apparent sign of which is megaloblastic anemia, caused by inhibited mitosis of red blood cells.9 Some individuals, especially those with malabsorption or low dietary intake, are at higher risks for a B12 deficiency. B12 in sublingual form, at a dose of 1000 mcg per day bypasses active absorption routes, and can restore normal B12 levels even in those with gastric bypass, pernicious anemia and\/or impaired absorptive capacity, with greater effectiveness than even intramuscular injection\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Sublingual Tablets","offer_id":40627024592919,"sku":"9420","price":11.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/B121000.jpg?v=1749226096"},{"product_id":"bioclinic-naturals-b12-methylcobalamin-5000-mcg","title":"Bioclinic Naturals B12 Methylcobalamin - 5000 mcg","description":"\u003cdiv class=\"uses_benefits\" data-mce-fragment=\"1\"\u003e\n\u003cul class=\"feature-list\" data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eMethylcobalamin is the active form of vitamin B12 for maximum benefit\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSuperior bioavailability to the more common form, cyanocobalamin, which does not convert to enough methylcobalamin to correct some forms of anemia, neurological defects, and aging1\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eLowers homocysteine levels for protective cardiovascular benefits\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSublingual tablets allow for fast acting delivery system directly into blood stream\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"feature_summary\" data-mce-fragment=\"1\"\u003e\n\u003ch3 data-mce-fragment=\"1\"\u003eFeature Summary\u003c\/h3\u003e\n\u003cp data-mce-fragment=\"1\"\u003eVitamin B12 is the cofactor in enzymatic reactions with diverse physiological functions. It is required for the conversion of methylmalonyl CoA to succinyl CoA, as well as for the conversion of homocysteine to methionine by methionine synthase, which is then converted into S-adenosylmethionine.\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eA B12 deficiency causes impairments in both of these pathways, disrupting neurological function, including poor formation of myelin nerve sheaths, production of toxic levels of homocysteine, and inefficient energy production in all cells.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eMethylcobalamin, the principal circulating form of B12 and the one transported into peripheral tissues, has been shown to not only reduce homocysteine, but also to reduce inflammatory factors and the volume of carotid artery plaques among stroke patients, as well as pain, and neuropathy among diabetics.\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eBecause of its relationship to myelin production and neurological function, high dose B12 has been used in a variety of neurodegenerative diseases, including Parkinson’s disease, amyotrophic lateral sclerosis, and multiple sclerosis.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eSome individuals, especially those with malabsorption or low dietary intake, are at higher risks for a B12 deficiency. Individuals with impaired absorption of B12 rely on passive absorption, which is typically 1% of the ingested amount. Thus, high doses may be required for those with greater B12 needs, such as elderly individuals and those with neurodegenerative disorders.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Bioclinic Naturals","offers":[{"title":"60 Sublingual Tablets","offer_id":40627024658455,"sku":"9422","price":19.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/b125000.jpg?v=1749226096"},{"product_id":"pure-encapsulations-b12-5000-liquid","title":"Pure Encapsulations B12 5000 Liquid","description":"\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eHelps the body metabolize nutrients and form red blood cells\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eConvenient liquid format free of added colour or artificial sugars\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eMethylcobalamin is an activated, highly bioavailable form of vitamin B\u003csub data-mce-fragment=\"1\"\u003e12\u003c\/sub\u003e, which acts as the principal circulating form of cobalamin in the body. In general, vitamin B\u003csub data-mce-fragment=\"1\"\u003e12\u003c\/sub\u003e\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eworks with folate to promote red blood cell formation. Additionally, vitamin B\u003csub data-mce-fragment=\"1\"\u003e12\u003c\/sub\u003e\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eis an important cofactor for energy metabolism. One vitamin B\u003csub data-mce-fragment=\"1\"\u003e12\u003c\/sub\u003e-dependent enzyme is methylmalonyl-CoA mutase, which is involved in the formation of succinyl-CoA, a key Krebs cycle intermediate. Vitamin B\u003csub data-mce-fragment=\"1\"\u003e12\u003c\/sub\u003e\u003cspan data-mce-fragment=\"1\"\u003e \u003c\/span\u003eis also a vital component of the methionine synthase pathway.\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"30 mL","offer_id":41096197242903,"sku":"B125LC-C","price":40.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/b12-5-000-liquid-b125lc-c.jpeg.mst_1.webp?v=1749225851"},{"product_id":"biotics-research-b12-2000-lozenges","title":"Biotics Research B12 2000 Lozenges","description":"\u003cdiv class=\"product-note indented\"\u003e\n\u003cdiv class=\"note-descr\"\u003e\n\u003cdiv class=\"product-note indented\"\u003e\n\u003cdiv class=\"note-descr\"\u003e\n\u003cdiv\u003e\n\u003cp\u003eInflammation diabetes neuromuscular disorders elevated MCV\/MCH vegetarian diet. \u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-fields-wrapper indented vs-qty clearfix\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003c!----\u003e","brand":"Biotics Research","offers":[{"title":"60 Lozenges","offer_id":41524146339863,"sku":null,"price":48.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/1130-web-CAN.png?v=1762922407"},{"product_id":"cyto-matrix-bio-b-matrix-hp","title":"Cyto-Matrix Bio-B Matrix HP","description":"\u003cul class=\"list-disc text-lg leading-relaxed text-gray-600 pl-6\"\u003e\n\u003cli\u003eA high potency B-vitamin complex with active and bioavailable forms, including benfotiamine as a fat-soluble form of vitamin B1 for additional nerve and blood sugar support.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"list-disc list_points text-lg leading-relaxed text-gray-600\"\u003e\n\u003cul\u003e\n\u003cli\u003eA high potency blend of B-vitamins, in their metabolically active and highly bioavailable forms such as pyridoxal-5-phosphate (B6), methylcobalamin (B12) and 5-methyltetrahydrofolate (5-MTHF; B9)\u003c\/li\u003e\n\u003cli\u003eIncludes benfotiamine, a fat-soluble version of vitamin B1, which has been demonstrated to achieve higher peak blood levels, greater bioavailability (AUC) and improved uptake into brain, muscle, liver and kidney tissues\u003c\/li\u003e\n\u003cli\u003eAlso contains inositol, a key molecule in improving receptor sensitivity of neurotransmitters and hormones, and choline, a neurotrophic factor necessary for proper neurological development\u003c\/li\u003e\n\u003cli\u003eRecommended full daily dose is 3 capsules per day for optimal support\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c!----\u003e","brand":"Cyto-Matrix","offers":[{"title":"90 Vegetable capsules","offer_id":41606798376983,"sku":"193238","price":56.91,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/Bio-BMatrixHP.png?v=1749225655"},{"product_id":"cyto-matrix-bio-b-matrix-lt","title":"Cyto-Matrix Bio- B Matrix LT","description":"\u003cul class=\"list-disc text-lg leading-relaxed text-gray-600 pl-6\"\u003e\n\u003cli\u003eA complete blend of active B-vitamins with added L-Theanine and spirulina for patients with low energy, mental health concerns, stress and cognitive impairment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"list-disc list_points text-lg leading-relaxed text-gray-600\"\u003e\n\u003cul\u003e\n\u003cli\u003eA comprehensive blend of B-vitamins in their metabolically active and highly bioavailable forms\u003c\/li\u003e\n\u003cli\u003e100mg of L-theanine per capsule, for mood and stress support through alpha-brain wave induction\u003c\/li\u003e\n\u003cli\u003e60mg per capsule of spirulina, the blue-green algae that supplies a rich source of phytonutrients, carotene and additional B vitamins\u003c\/li\u003e\n\u003cli\u003e100mg of myo-inositol per capsule, to balance mood through improved receptor sensitivity of neurotransmitters and hormones\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c!----\u003e","brand":"Cyto-Matrix","offers":[{"title":"60 Vegetable capsules","offer_id":41606814105623,"sku":"193157","price":36.01,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/CM-Bio-BMatrixLT.png?v=1749225655"},{"product_id":"cyto-matrix-cyto-b12-500mcg-drops","title":"Cyto-Matrix Cyto-B12 - 500mcg Drops","description":"\u003cul class=\"list-disc text-lg leading-relaxed text-gray-600 pl-6\"\u003e\n\u003cli\u003e\n\u003cp\u003e500mcg of methylcobalamin per liquid drop in a natural blueberry flavour.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv class=\"list-disc list_points text-lg leading-relaxed text-gray-600\"\u003e\n\u003cul\u003e\n\u003cli\u003eSigns and symptoms of vitamin B12 deficiency include fatigue, cognitive decline, mood changes, peripheral neuropathy, restless leg syndrome, macrocytic anemia and hyperhomocysteinemia\u003c\/li\u003e\n\u003cli\u003eSupplemental vitamin B12 can be found in multiple forms, although methylcobalamin is the form predominantly found in plasma and cerebrospinal fluid\u003c\/li\u003e\n\u003cli\u003eMethylcobalamin specifically has been studied for its ability to improve peripheral neuropathy, multiple sclerosis, low mood and cognitive decline\u003c\/li\u003e\n\u003cli\u003eEach drop provides 500mcg of stable methylcobalamin in a natural blueberry flavour\u003c\/li\u003e\n\u003cli\u003eVegan and free from dairy, gluten, soy and GMOs\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c!----\u003e","brand":"Cyto-Matrix","offers":[{"title":"15 ml","offer_id":41606921125911,"sku":"193255","price":26.41,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/1646852613_CM-Cyto-B12drops-15ml-RGB-193255-V1_352_420.png?v=1749225655"},{"product_id":"nfh-l-5-mthf-sap","title":"NFH L-5-MTHF SAP","description":"\u003cp\u003e\u003cspan\u003eFolic acid, or folate, is a B vitamin that must be derived from either dietary sources or via supplementation. 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Folate is found in leafy green vegetables, legumes, beans, liver, yeast, and citrus fruits. \u003c\/span\u003e\u003c\/p\u003e","brand":"NFH","offers":[{"title":"60 Capsules","offer_id":41741092683799,"sku":"NFH1100","price":23.7,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/8922\/6775\/files\/0000218_l-5-mthf-sap_625.jpg?v=1749225652"},{"product_id":"thorne-b-complex-7","title":"Thorne B-Complex #6","description":"\u003cp\u003e\u003cspan\u003eB-Complex #6 contains a balance of essential B vitamins, including methylated B12 and folate, with added B6 for sports performance. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eRecommended Use or Purpose: A multi-vitamin supplement that is a factor in the maintenance of good health. Helps to maintain cognitive functions. Helps to maintain the body's ability to metabolize nutrients. Helps in energy production. Helps in the normal function of the immune system. 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